Screen for anemia if: 1. Preterm or low–birth-weight infants 2. Infants receiving unfortified formula 3. Infants receiving cow's milk before age 12 months 4. Breastfed infants not getting iron supplementation after age 6 months 5. Children consuming >24 oz cow's milk per day 6. Children with special health care needs Tx & Recs For mild microcytic anemia (ie, hemoglobin = 8 to 10 g/dL), empiric treatment with iron supplementation (3 to 4 mg elemental iron/kg/day) is appropriate. -The reticulocyte count should increase within 1 week of beginning iron therapy, and the hemoglobin should rise by at least 1 g/dL within a month. (recheck in 1-2months) -Treatment should continue in patients who respond for an additional 2 months to ensure adequate replacement of iron stores. -For patients who fail to respond, additional laboratory evaluation is indicated, and referral to a hematologist should be considered. -Appropriate dietary counseling is important to prevent recurrence. An evaluation should be undertaken to identify sources of occult blood loss that may be contributing to the iron deficiency, particularly in older children who are not consuming inordinate amounts of cow's milk. -If the anemia is more severe, then confirmatory laboratory evaluation should be obtained at the time empiric iron therapy is begun.