Down Syndrome: Referrals: -Cardiology for Echo (AV canal 50%, VSD 33%) -Ophthalmology b/w 6-12mo; then q2yrs -GI (or studies for GI Abnormalities -Hirshprungs, Esophageal atresia, TEF, PS, Duodenal atresia (only 4%)) -Polycythemia occurs in about 18% -typically self limiting occassionally requires exchange transfusion